Filtering by
- All Subjects: Deep learning
- Creators: Computer Science and Engineering Program
Molecular pathology makes use of estimates of tumor content (tumor percentage) for pre-analytic and analytic purposes, such as molecular oncology testing, massive parallel sequencing, or next-generation sequencing (NGS), assessment of sample acceptability, accurate quantitation of variants, assessment of copy number changes (among other applications), determination of specimen viability for testing (since many assays require a minimum tumor content to report variants at the limit of detection) may all be improved with more accurate and reproducible estimates of tumor content. Currently, tumor percentages of samples submitted for molecular testing are estimated by visual examination of Hematoxylin and Eosin (H&E) stained tissue slides under the microscope by pathologists. These estimations can be automated, expedited, and rendered more accurate by applying machine learning methods on digital whole slide images (WSI).
This research paper explores the effects of data variance on the quality of Artificial Intelligence image generation models and the impact on a viewer's perception of the generated images. The study examines how the quality and accuracy of the images produced by these models are influenced by factors such as size, labeling, and format of the training data. The findings suggest that reducing the training dataset size can lead to a decrease in image coherence, indicating that AI models get worse as the training dataset gets smaller. Moreover, the study makes surprising discoveries regarding AI image generation models that are trained on highly varied datasets. In addition, the study involves a survey in which people were asked to rate the subjective realism of the generated images on a scale ranging from 1 to 5 as well as sorting the images into their respective classes. The findings of this study emphasize the importance of considering dataset variance and size as a critical aspect of improving image generation models as well as the implications of using AI technology in the future.
Breast cancer is one of the most common types of cancer worldwide. Early detection and diagnosis are crucial for improving the chances of successful treatment and survival. In this thesis, many different machine learning algorithms were evaluated and compared to predict breast cancer malignancy from diagnostic features extracted from digitized images of breast tissue samples, called fine-needle aspirates. Breast cancer diagnosis typically involves a combination of mammography, ultrasound, and biopsy. However, machine learning algorithms can assist in the detection and diagnosis of breast cancer by analyzing large amounts of data and identifying patterns that may not be discernible to the human eye. By using these algorithms, healthcare professionals can potentially detect breast cancer at an earlier stage, leading to more effective treatment and better patient outcomes. The results showed that the gradient boosting classifier performed the best, achieving an accuracy of 96% on the test set. This indicates that this algorithm can be a useful tool for healthcare professionals in the early detection and diagnosis of breast cancer, potentially leading to improved patient outcomes.
In addition to an identification network, a new sampling-based motion planner, Learn and Link, is introduced. This planner leverages critical regions to overcome the limitations of uniform sampling while still maintaining guarantees of correctness inherent to sampling-based algorithms. Learn and Link is evaluated against planners from the Open Motion Planning Library (OMPL) on an extensive suite of challenging navigation planning problems. This work shows that critical areas of an environment are learnable, and can be used by Learn and Link to solve MP problems with far less planning time than existing sampling-based planners.
This work proposes a deep learning approach that identifies critical regions in the environment and learns a sampling distribution to effectively sample them in high dimensional configuration spaces.
A classification-based approach is used to learn the distributions. The robot degrees of freedom (DOF) limits are binned and a distribution is generated from sampling motion plan solutions. Conditional information like goal configuration and robot location encoded in the network inputs showcase the network learning to bias the identified critical regions towards the goal configuration. Empirical evaluations are performed against the state of the art sampling-based motion planners on a variety of tasks requiring the robot to pass through critical regions. An empirical analysis of robotic systems with three to eight degrees of freedom indicates that this approach effectively improves planning performance.
