Matching Items (654)
Description
Background: Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer deaths in females worldwide, accounting for 23% of all new cancer cases and 14% of all total cancer deaths in 2008. Five tumor-normal pairs of primary breast epithelial cells were treated for infinite proliferation by using a ROCK inhibitor and mouse feeder cells. Methods: Raw paired-end, 100x coverage RNA-Seq data was aligned to the Human Reference Genome Version 19 using BWA and Tophat. Gene differential expression analysis was completed using Cufflinks and Cuffdiff. Interactive Genome Viewer was used for data visualization. Results: 15 genes were found to be down-regulated by at least one log-fold change in 4/5 of tumor samples. 75 genes were found to be down-regulated in 3/5 of our tumor samples by at least one log-fold change. 11 genes were found to be up-regulated in 4/5 of our tumor samples, and 68 genes were identified to be up-regulated in 3/5 of the tumor samples by at least one-fold change. Conclusion: Expression changes in genes such as AZGP1, AGER, ALG11, and S1007 suggest a disruption in the glycosylation pathway. No correlation was found between Cufflink's Her2 gene-expression and DAKO score classification.
ContributorsHernandez, Fernando (Author) / Anderson, Karen (Thesis director) / Mangone, Marco (Committee member) / Park, Jin (Committee member) / Barrett, The Honors College (Contributor) / Department of Information Systems (Contributor)
Created2013-05
DescriptionFeatures projects advancing women of color in the tech field.
ContributorsArizona State University. Center for Gender Equity in Science and Technology (Contributor)
Created2020-20-21
Description
Features projects advancing women of color in the tech field.
ContributorsArizona State University. Center for Gender Equity in Science and Technology (Contributor)
Created2020
Description
Features projects advancing women of color in the tech field.
ContributorsArizona State University. Center for Gender Equity in Science and Technology (Contributor)
Created2021
Description
Features projects advancing women of color in the tech field.
ContributorsArizona State University. Center for Gender Equity in Science and Technology (Contributor)
Created2021
Description
Features projects advancing women of color in the tech field.
ContributorsArizona State University. Center for Gender Equity in Science and Technology (Contributor)
Created2021
Description
Features projects advancing women of color in the tech field.
ContributorsArizona State University. Center for Gender Equity in Science and Technology (Contributor)
Created2021
DescriptionProvides results of a national study of digital technology use among African American teens and their parents.
ContributorsRideout, Victoria J. (Author) / Scott, Kimberley A., Ed.D. (Author) / Clark, Kevin A., Ph.D. (Author) / Arizona State University. Center for Gender Equity in Science and Technology (Contributor)
Created2016
DescriptionProvides results of a study that examined the effects of a girl-centered culturally responsive educational program on self-concept.
ContributorsTao, Chun, M.S. (Author) / Scott, Kimberly Ann, 1969- (Contributor) / Arizona State University. Center for Gender Equity in Science and Technology (Contributor)
Created2017 (year uncertain)
Description
This report analyzes the intersection that is present between law and technology. It covers the basics of patents and intellectual property law, and then touches briefly about the software side of patent law. The future of patent and technology law are explored as well. The main focus of this report is the patent that was created for a beacon that provides for a full enterprise resource planning solution at both supply chain and full business levels.
ContributorsShah, Dhara Vimesh (Author) / Michelle, Gross (Thesis director) / Stevens, Yvonne (Committee member) / Department of Information Systems (Contributor) / W. P. Carey School of Business (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12