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In 2012, Stephen Sidney, T. Craig Cheetham, FrederickA. Connell, and colleagues published "Recent Combined Hormonal Contraceptives (CHCs) and the Risk of Thromboembolism and Other Cardiovascular Events in New Users," hereafter "Combined Hormonal Contraceptives" in Contraception. The authors gathered records of major cardiovascular events in patients who were using combined hormonal

In 2012, Stephen Sidney, T. Craig Cheetham, FrederickA. Connell, and colleagues published "Recent Combined Hormonal Contraceptives (CHCs) and the Risk of Thromboembolism and Other Cardiovascular Events in New Users," hereafter "Combined Hormonal Contraceptives" in Contraception. The authors gathered records of major cardiovascular events in patients who were using combined hormonal contraceptive treatments, or CHCs. A CHC is a birth control medication that contains both estrogen and progestin hormones. The CHCs of focus, which the authors referred to as the study CHCs, included a pill, patch, and vaginal ring that the US Food and Drug Administration, or FDA, recently approved at the time of publication. The researchers compared the rates of cardiovascular events between users of the study CHCs to users of established CHCs to find any increased cardiovascular risk. "Combined Hormonal Contraceptives" showed that the study CHCs did come with some increased cardiovascular risk, and reconfirmed the known cardiovascular risks of CHCs in general, providing safety information for people who may want to start birth control.

ContributorsPillai, Megha (Editor) / Jacobson, Molly (Author)
Created2024-05-29
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Arnold Henry Kegel worked and carried out research in the medical field of gynecology in the US during the twentieth century. Through his work, Kegel was one of the first to describe what researchers call Kegel exercises, which strengthen the pelvic floor muscles, or the muscles that extend from the

Arnold Henry Kegel worked and carried out research in the medical field of gynecology in the US during the twentieth century. Through his work, Kegel was one of the first to describe what researchers call Kegel exercises, which strengthen the pelvic floor muscles, or the muscles that extend from the pelvis to the tailbone and support the internal reproductive organs, bladder, and bowel. Kegel observed that weakened pelvic floor muscles could cause disorders like urinary incontinence, when a person loses partial or complete bladder control, and pelvic organ prolapse, which is when the pelvic floor cannot adequately support organs in the pelvic region, causing them to fall out of place. Kegel was also one of the first to find that females could strengthen their pelvic floors through exercises, which provided an alternative to invasive surgeries to repair those muscles. Kegel helped discern the role that the pelvic floor plays in reproductive health, and he developed simple methods to strengthen the pelvic floor that could, in turn, improve sexual and reproductive health in females and males of all ages.
ContributorsJohnson,Madelyn (Author) / Pillai, Megha (Editor)
Created2024-05-29
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Hideyo Noguchi researched bacteria, including Treponema pallidum, the bacterium that causes syphilis, in Japan and the US during the early 1900s. Syphilis is a bacterial infection that spreads primarily through sexual transmission and can cause symptoms such as rashes, genital sores, and even organ damage. Noguchi recognized that Treponema pallidum

Hideyo Noguchi researched bacteria, including Treponema pallidum, the bacterium that causes syphilis, in Japan and the US during the early 1900s. Syphilis is a bacterial infection that spreads primarily through sexual transmission and can cause symptoms such as rashes, genital sores, and even organ damage. Noguchi recognized that Treponema pallidum causes neurosyphilis, which is when the syphilis infection spreads to the covering of the brain, the brain itself, or the spinal cord. Before Noguchi's work, researchers knew about Treponema pallidum and the symptoms of the disease but did not know that untreated syphilis could lead to neurosyphilis. Additionally, Noguchi worked to alter and improve methods to diagnose syphilis. Noguchi's work helped future researchers and doctors better diagnose people with syphilis and assisted them in understanding how to treat the disease's long-term side effects.
ContributorsSwaminathan,Srivatsan (Author) / Pillai, Megha (Editor)
Created2024-05-30
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Metoidioplasty is a type of gender-affirming surgery that creates a small-sized neophallus, or new penis, from an enlarged clitoris. Gender-affirmation surgeries are procedures that alter a person's body, typically sexual characteristics like the genitals, to align a person's sex with their gender identity so that they can move through society

Metoidioplasty is a type of gender-affirming surgery that creates a small-sized neophallus, or new penis, from an enlarged clitoris. Gender-affirmation surgeries are procedures that alter a person's body, typically sexual characteristics like the genitals, to align a person's sex with their gender identity so that they can move through society more comfortably. Such procedures treat gender dysphoria, which is the distress or discomfort that may be felt by transgender people. Transgender people's gender identities differ from the genders they were assigned at birth, usually conflated with the sex they were assigned at birth. As opposed to aphalloplasty, a procedure where a neophallus is created using tissue from other areas of the body and not just the existing genital tissues, metoidioplasty allows transgender individuals to have a penis with less noticeable scarring, preservation of erogenous sensation, and, if the patient desires, the ability to urinate while standing. The technique was first suggested in 1973, then performed in 1974, however, doctors and researchers did not refer to it as metoidioplasty until 1989. Since its implementation, several modifications have ensured lower risks and better results for patients. Metoidioplasty improves the quality of life for people seeking gender-affirmation surgery by treating gender dysphoria.
ContributorsMcInnis,Riley (Author) / Nichols, Cole (Editor)
Created2024-05-30
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A vasectomy is a surgery that works to inhibit reproduction by interrupting the passage of sperm through the vas deferens, a tube in the male reproductive system. The procedure is a method of inhibiting an individual's ability to cause pregnancy through sexual intercourse without altering the other functions of the

A vasectomy is a surgery that works to inhibit reproduction by interrupting the passage of sperm through the vas deferens, a tube in the male reproductive system. The procedure is a method of inhibiting an individual's ability to cause pregnancy through sexual intercourse without altering the other functions of the penis and testes. In the US, into the early 1900s, proponents of eugenics, the belief that human populations can be made better by selecting for so-called desirable traits, used the procedure to forcibly sterilize people whom they deemed undesirable. Despite its early associations with eugenics, physicians' use of vasectomy eventually transitioned into an option for elective contraception. Even with the various shifts in motivation for performing vasectomies, as of 2024, individuals have the choice to undergo a sterilization procedure if they want to restrict their own ability to have children.

ContributorsNichols,Cole (Author) / Pillai, Megha (Editor)
Created2024-05-31
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On 22 March 1972, in Eisenstadt v. Baird, hereafter Eisenstadt, the United States Supreme Court determined, in a six to one decision, that unmarried individuals have the same right to access contraceptives as married couples.Eisenstadt involved William Baird, a reproductive rights advocate who intentionally broke Massachusetts law in 1967 by

On 22 March 1972, in Eisenstadt v. Baird, hereafter Eisenstadt, the United States Supreme Court determined, in a six to one decision, that unmarried individuals have the same right to access contraceptives as married couples.Eisenstadt involved William Baird, a reproductive rights advocate who intentionally broke Massachusetts law in 1967 by giving a speech about birth control at Boston University in Boston, Massachusetts, and giving an unmarried, nineteen-year-old woman contraceptives. Baird argued that laws against unmarried people accessing contraceptives unfairly discriminated against unmarried people and denied them reproductive autonomy. Massachusetts law, however, stated that contraceptives could only be distributed by medical professions to married people. The case followed a similar legal challenge from 1965, Griswold v. Connecticut, hereafter Griswold, which found that married individuals have the right to access contraceptives based on a constitutional right to privacy in the US.Eisenstadt reinforced the constitutional right to privacy and equalized the accessibility to contraceptives for married and single individuals.

ContributorsRoss,Nathaniel (Author) / Pinteric, Aubrey (Editor)
Created2024-06-04
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On 1 February 1998, David T. Helm, Sara Miranda, and Naomi Angoff Chedd published "Prenatal Diagnosis of Down Syndrome: Mothers' Reflections on Supports Needed From Diagnosis to Birth," hereafter "Mothers' Reflections," in the journal Mental Retardation. In 2007,Mental Retardation changed its name toIntellectual and Developmental Disabilities.Down syndrome is the result

On 1 February 1998, David T. Helm, Sara Miranda, and Naomi Angoff Chedd published "Prenatal Diagnosis of Down Syndrome: Mothers' Reflections on Supports Needed From Diagnosis to Birth," hereafter "Mothers' Reflections," in the journal Mental Retardation. In 2007,Mental Retardation changed its name toIntellectual and Developmental Disabilities.Down syndrome is the result of an extra copy or partial copy of chromosome 21, also known as Trisomy 21. It is characterized by traits such as intellectual disabilities, differing facial features, and a high risk for heart disease. In the study, the authors interviewed ten mothers, all of whom had elected to continue with their pregnancy after a prenatal diagnosis of Down syndrome, about their experiences with health care professionals. The article provides suggestions for health care professionals, such as providing up-to-date materials and unbiased information and avoiding judgmental language, so that when mothers receive a prenatal diagnosis of a developmental disability, they are prepared and supported.
ContributorsRauch,Grace (Author) / Pillai, Megha (Editor)
Created2024-06-04
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On 7 June 1965, in Griswold v. Connecticut (1965), the United States Supreme Court decided, in a seven to two decision, that married couples have the right to purchase and usecontraceptiveswithout government restriction. The case considered the constitutionality of a Connecticut state statute from 1879 that prohibited the sale or

On 7 June 1965, in Griswold v. Connecticut (1965), the United States Supreme Court decided, in a seven to two decision, that married couples have the right to purchase and usecontraceptiveswithout government restriction. The case considered the constitutionality of a Connecticut state statute from 1879 that prohibited the sale or use of any contraceptive device or medication. In 1961, Estelle Griswold, an executive director of the Planned Parenthood League of Connecticut, hereafter PPLC, and physician Charles Lee Buxton were convicted for selling contraceptives at a pregnancy clinic they opened in New Haven, Connecticut, in violation of state law. Griswold and Buxton challenged the constitutionality of the Connecticut law, claiming it violated the Due Process Clause of the Fourteenth Amendment of the US Constitution, which states that the state government cannot infringe upon rights of citizens without a fair process, such as a trial.Griswold v. Connecticuthelped establish an inferred right to privacy within the amendments of the US constitution, granting the right of married couples to access contraceptives and setting the foundation for future cases involving contraception, abortion, anti-sodomy laws, and marriage.
ContributorsRoss,Nathaniel (Author) / Shah, Devangana (Editor)
Created2024-06-05
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Henry Hubert Turner was a physician and researcher who studied hormones and human development in Oklahoma City, Oklahoma, during the twentieth century. He was one of the first people to classify Turner syndrome, which is a genetic condition that occurs when someone has a specific atypical chromosomal pattern, and as

Henry Hubert Turner was a physician and researcher who studied hormones and human development in Oklahoma City, Oklahoma, during the twentieth century. He was one of the first people to classify Turner syndrome, which is a genetic condition that occurs when someone has a specific atypical chromosomal pattern, and as of 2024, affects one in 1,500 to 2,500 female births. Turner syndrome results in a biological female completely or partially missing one of their X chromosomes. Many researchers label it an intersex condition, or a condition in which someone has atypical male or female sex characteristics, such as different sex chromosome patterns. During his career, Turner encountered multiple patients with a specific set of symptoms, including stunted sexual development, webbed neck, and elbow deformities, and he was unable to place those symptoms under one existing diagnosis. So, he categorized those symptoms as a new syndrome, which researchers later named Turner syndrome. By identifying Turner syndrome as a developmental condition, Turner helped future physicians develop treatments and diagnostic tools that can improve the lives of individuals with various developmental disorders.
ContributorsPillai,Megha (Author) / Nichols,Cole (Editor)
Created2024-06-06
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The DTaP vaccination series is an FDA-approved, five-shot vaccine for young children in the United States for protection against diphtheria, tetanus, and pertussis. DTaP stands for diphtheria, tetanus, and acellular pertussis, which are all common childhood diseases. In the US, Daptacel and Infanrix are the two types of DTaP vaccines,

The DTaP vaccination series is an FDA-approved, five-shot vaccine for young children in the United States for protection against diphtheria, tetanus, and pertussis. DTaP stands for diphtheria, tetanus, and acellular pertussis, which are all common childhood diseases. In the US, Daptacel and Infanrix are the two types of DTaP vaccines, whereas other countries offer other variations. Both Daptacel and Infanrix consist of five shots that stimulate the immune system to protect a child against those diseases. Children vaccinated with DTaP may still end up getting one of the diseases, but they often present with milder symptoms than if they were not vaccinated. The general vaccination schedule for the five shot series is two months, four months, six months, fifteen to eighteen months, and four to six years of age. DTaP vaccination fully protects nine out of ten children against acquiring disease, contributing to a downward trend in diphtheria, tetanus, and pertussis cases in developing children in the US.
ContributorsZhou,Maggie (Author) / Nichols, Cole (Editor)
Created2024-06-21